Tuesday, August 28

Idebenone in Anti-aging Skin Care Products

We are used to thinking anti-oxidants as part of dietary supplements to slow down the aging process and keep one’s appearance healthy and younger-looking. But do you know one of the most active ingredients in the best anti-aging skin care products are antioxidants?

Sources of antioxidants like Ascorbyl Palmitate (a form of fat soluble Vitamin C) and tea green extracts which contain catechin polyphenols have been used to manufacture the best anti-aging creams and serums, but the most potent of the six leading antioxidants is Idebenone.

From the Journal of Cosmetic Dermatology, in a study done by a group of researchers who developed the first ever protocol to compare the efficacy of antioxidants on their effects on preventing free-radical skin-damage, Idebenone received a score of 95 out of a 100, which was the highest score among the six leading antioxidants.

Idebenone is a synthetic analogue of a naturally-occurring enzyme called Coenzyme Q10 (Co Q10). Co Q10 is an important antioxidant component of the lipid (fatty) membranes that surround all cells, as well as the lipid membranes surrounding the various organelles ("little organs"), such as mitochondria and microsomes, inside cells. It is cell energizer, which means it produces the required energy for cell reproduction.

However, Idebenone is different from Coenzyme Q10 in one very important way. During a hypoxic (low oxygen) condition, CoQ10 can switch function from an anti-oxidizing to an auto-oxidizing process. This auto-oxidation rapidly produces free radicals which damage the tissues of the body. Studies have shown that in such circumstances Idebenone prevents the free radical damage and maintains relatively normal cell ATP levels.

In order to understand how Idebenone provides anti-aging benefits we must read about mitochondrial processes in cells. The mitochondrial power plants produce over 90% of all cellular ATP bioenergy. They are also generally the richest sites in Co Q10 (or Idebenone). Mitochondrial DNA (mtDNA) allows mitochondria to reproduce themselves.

Over the course of a lifetime our mtDNA becomes ever more damaged, and the mitochondria produced become ever more ineffective in their energy generation. The cells that are most susceptible to mitochondrial energy depletion with advancing age are the brain, skeletal muscle and heart muscle cells. As a result our cells die and various diseases develop in our advanced years.

Idebenone, therefore, provides an anti-aging effect here in several ways. Unlike Co Q10, even under the low oxygen conditions that may occur periodically over a lifetime, Idebenone will serve as a powerful mitochondrial free radical quencher, lessening the ever-increasing mtDNA damage that occurs with age. Idebenone will work even better than Co Q10 within the electron transport chain to keep energy production high, even under hypoxic conditions.

With Idebenone used as a powerful active ingredient in anti-aging products, users are assured that the best antiwrinkle creams and serums can deliver the results they expect without the harmful side effects of free radical production.

Check out the best anti-wrinkle cream reviews before you buy anything. Knowing what works and what doesn’t can help you avoid spending on an anti-aging skin care product that is ineffective and basically worthless.

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